Please ensure Javascript is enabled for purposes of website accessibility
Home > Products > Antibodies > Flow Cytometry (FACS) Antibodies

Anti-Human CD282/TLR2 Antibody (OPN-305), FITC (HT188117)

Price(USD): $
Spec:
  • 50T
  • 100T
Number:
Contact us
  • Overview

  • Images

  • References

  • Datasheet

Overview
Catalog No.HT188117
Description
Anti-Human CD282/TLR2 Antibody (OPN-305), FITC [OPN-305] (HT188117) is a human monoclonal antibody detecting CD282 in FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
  • Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
IsotypeIgG4, kappa
Clone IDOPN-305
ConjugationFITC
Clonality Monoclonal
Target TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282
Endotoxin level Please contact with the lab for this information.
Accession O60603
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also activate immune cells and promote apoptosis in response to the lipid moiety of lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

1. Jin, MS. et al. (2007) Cell 130, 1071-82. PMID: 17889651
2. Lancioni, CL. et al. (2011) Infection and immunity 79, 663-73. PMID: 21078852
3. Brightbill, HD. et al. (1999) Science (New York, N.Y.) 285, 732-6. PMID: 10426995
4. Aliprantis, AO. et al. (1999) Science (New York, N.Y.) 285, 736-9. PMID: 10426996
5. Bulut, Y. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 987-94. PMID: 11441107
6. Jung, SB. et al. (2006) Infection and immunity 74, 2686-96. PMID: 16622205
7. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712
8. Bulut, Y. et al. (2005) The Journal of biological chemistry 280, 20961-7. PMID: 15809303
9. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
Images
References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommendation

Contact us for custom quotes, bulk requests and any other issues.

Mail: support@abinScience.com

Distributor list