Anti-Mouse CD35/CR1/CD21b Antibody (7G6), APC (MB625137)

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Overview

Catalog No.	MB625137
Description	Anti-Mouse CD35/CR1/CD21b Antibody (7G6), APC [7G6] (MB625137) is a rat monoclonal antibody detecting CD35 in ELISA, FCM. Suitable for Mouse. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Mouse
Applications	ELISA, FCM
Host species	Rat
Isotype	IgG2b, kappa
Clone ID	7G6
Conjugation	APC
Clonality	Monoclonal
Target	C3BR, Complement receptor type 1, CR1, CD35, C3b/C4b receptor
Endotoxin level	Please contact with the lab for this information.
Accession	Q64735
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Complement component receptor 1-like protein (CD35/CR1) is a ~53 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD35/CR1/CD21b Antibody (7G6), APC.pdf

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Anti-Mouse CD35/CR1/CD21b Antibody (7G6), APC (MB625137)

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