

| Catalog No. | HB103137 |
|---|---|
| Description |
Anti-Human CD32b/FCGR2B Antibody (SAA0547), APC [SAA0547] (HB103137) is a human monoclonal antibody detecting FCGR2B in ELISA, FCM, WB. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, FCM, WB |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | SAA0547 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | IGFR2, FCG2, Fc-gamma RII-b, CDw32, FcRII-b, IgG Fc receptor II-b, CD32, Fc-gamma-RIIb, Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, RHD97901 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P31994 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Low affinity immunoglobulin gamma Fc region receptor II-b (CD32b/FCGR2B) is a ~34 kDa protein. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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