Normal Rat IgG Recombinant Isotype Control Antibody, PE (RF690127)

Name: Normal Rat IgG Recombinant Isotype Control Antibody, PE
Brand: abinScience
SKU: RF690127
Price: 110 USD
Availability: InStock

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Overview

Catalog No.	RF690127
Description	Normal Rat IgG Recombinant Isotype Control Antibody, PE (RF690127) is a rat polyclonal antibody detecting IgG in FCM, Isotype Control. Suitable for Rat. Highlights ●Multi-Application — Validated across multiple applications. ●PE Conjugated — Ready for direct detection without secondary antibody.
Species reactivity	Rat
Applications	FCM, Isotype Control
Host species	Rat
Clonality	Polyclonal
Isotype	IgG
Conjugation	PE
Nature	Native
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Immunoglobulin heavy constant gamma 4 (IgG4) is a ~43 kDa protein. Constant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding to a specific antigen trigger the clonal expansion and differentiation of B lymphocytes into Ig-secreting plasma cells. Secreted Igs known as antibodies mediate the effector phase of humoral immunity by blocking the interaction of infectious antigens with cellular receptors (via the antigen-binding region) and eliciting effector mechanisms that lead to pathogen neutralization (via the constant region). The antigen-binding region is formed by the variable domain of one heavy chain paired with the variable domain of its associated light chain. 1. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 2. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 3. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.