

| Catalog No. | HY327127 |
|---|---|
| Description |
Anti-Human CCL4/MIP-1-beta Antibody (SAA0455), PE [SAA0455] (HY327127) is a mouse monoclonal antibody detecting MIP-1-beta in ELISA, FCM. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, FCM |
| Host species | Mouse |
| Isotype | IgG2a, kappa |
| Clone ID | SAA0455 |
| Conjugation | PE |
| Clonality | Monoclonal |
| Target | MIP-1-beta(1-69), MIP-1-beta, C-C motif chemokine 4, Protein H400, ACT-2, HC21, T-cell activation protein 2, Lymphocyte activation gene 1 protein, LAG-1, SIS-gamma, Small-inducible cytokine A4, G-26 T-lymphocyte-secreted protein, Macrophage inflammatory protein 1-beta, LAG1, PAT 744, CCL4, SCYA4, MIP1B |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P13236 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | C-C motif chemokine 4 (CCL4/MIP-1-beta) is a ~10 kDa protein. Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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