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Anti-Human DPEP3 Antibody (B43) (HV426107)

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Anti-Human DPEP3 Antibody (B43)

Anti-Human DPEP3 Antibody (B43)

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Overview

Catalog No.	HV426107
Description	Anti-Human DPEP3 Antibody (B43) [B43] (HV426107) is a mouse monoclonal antibody detecting DPEP3 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	B43
Clonality	Monoclonal
Target	DPEP3, Dipeptidase 3
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9H4B8
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Dipeptidase 3 (DPEP3) is a ~53 kDa protein. Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide. A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance. 1. Hayashi, K. et al. (2020) Journal of structural biology 211, 107512. PMID: 32325220
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human DPEP3 Antibody (B43)

References

Datasheet

Anti-Human DPEP3 Antibody (B43).pdf

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Anti-Human DPEP3 Antibody (B43)