Anti-Mouse MAdCAM-1 Recombinant Antibody (MECA-89) (MC589023)

Name: Anti-Mouse MAdCAM-1 Recombinant Antibody (MECA-89)
Brand: abinScience
SKU: MC589023
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	MC589023
Species reactivity	Mouse
Applications	IP, WP, Block, FCM, IHC
Host species	Rat
Clonality	Monoclonal
Isotype	IgG2a, kappa
Clone ID	MECA-89
Target	MAdCAM-1, Madcam1, Mucosal addressin cell adhesion molecule 1, mMAdCAM-1
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q61826
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is a ~43 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Note	For research use only

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Formula

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Overview