Siltuximab Antibody Pair Set (HY328918)

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Overview

Catalog No.	HY328918
Brand	abinScience
Description	Siltuximab Antibody Pair Set (HY328918) is a capture: mouse, detection: mouse antibody detecting Siltuximab in ELISA. Suitable for General. Highlights ●Detection: Biotin Conjugated — Ready for direct detection without secondary antibody.
Species reactivity	General
Host species	Capture: Mouse, Detection: Mouse
Immunogen	Siltuximab
Conjugation	Detection: Biotin
Tested applications	S-ELISA
Target	Siltuximab
Specificity	Siltuximab
Applications	ELISA
Form	Liquid
Storage buffer	Capture: 0.01M PBS pH 7.4; Detection: 0.01M PBS pH 7.4, 50% glycerol Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Assay type	Sandwich ELISA
Specifications	Reagents are sufficient for at least 1 x 96 well plates using recommended protocol.
Background	Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Note	For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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References

Datasheet

Siltuximab Antibody Pair Set.pdf

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Protocol

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

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