Nipah virus Glycoprotein G Antibody Pair Set (VK685918)

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Overview

Catalog No.	VK685918
Description	Nipah virus Glycoprotein G Antibody Pair Set (VK685918) is a capture: mouse, detection: human antibody detecting Glycoprotein G in ELISA. Suitable for Nipah virus (NiV). Highlights ●Detection: Biotin Conjugated — Ready for direct detection without secondary antibody.
Species reactivity	Nipah virus (NiV)
Host species	Capture: Mouse, Detection: Human
Immunogen	Glycoprotein G
Conjugation	Detection: Biotin
Tested applications	S-ELISA
Target	Glycoprotein G
Specificity	Glycoprotein G
Applications	ELISA
Form	Liquid
Storage buffer	Capture: 0.01M PBS pH 7.4; Detection: 0.01M PBS pH 7.4, 50% glycerol Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Assay type	Sandwich ELISA
Specifications	Reagents are sufficient for at least 1 x 96 well plates using recommended protocol.
Background	Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Note	For Research Use Only. Not for use in diagnostic or therapeutic procedures.