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InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#) (JN822010)

InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#)
InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#)
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  • 1mg
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Overview
Catalog No.JN822010
Description
InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#) [11E10#] (JN822010) is a human monoclonal antibody detecting rRNA N-glycosylase in ELISA, Neutralization. Suitable for Escherichia coli.
Species reactivityEscherichia coli
ApplicationsELISA, Neutralization
Host speciesHuman
IsotypeIgG1, kappa
Clone ID11E10#
Clonality Monoclonal
Target rRNA N-glycosylase, 3.2.2.22, stx2 A-subunit, stx-2 A subunit, stx2, stx2A, stx2a, stx2A_1, stx2cA, stx2vA, stxA2, stxA_1, stxA_3, vta, vtx2A, Escherichia coli
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Associated products pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Accession P09385
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Shiga-like toxin 2 subunit A (shiga toxin type 2A/stx2A) is a ~35 kDa protein. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.

Note For research use only. Not suitable for clinical or therapeutic use.
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  • InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#).

References
Formula
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