

| Catalog No. | VK665040 |
|---|---|
| Description |
InVivoMAb Anti-HCMV/HHV-5 gB/Envelope glycoprotein B Antibody (8F9) [8F9] (VK665040) is a human monoclonal antibody detecting Envelope glycoprotein B in ELISA, Neutralization.
|
| Species reactivity | Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5) |
| Applications | ELISA, Neutralization |
| Host species | Human |
| Isotype | IgG1 |
| Clone ID | 8F9 |
| Clonality | Monoclonal |
| Target | Envelope glycoprotein B, gB, gB, UL55 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P13201 |
| RRID | InVivoMAb Anti-HCMV/HHV-5 gB/Envelope glycoprotein B Antibody (8F9) (abinScience Cat# VK665040, RRID:AB_3729580) |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-HCMV/HHV-5 gB/Envelope glycoprotein B Antibody (8F9)




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