

| Catalog No. | VK006013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-HSV-1/HSV-2 gB Recombinant Antibody (SAA2248) (VK006013) is a human monoclonal antibody detecting gB in ELISA, Neutralization. Suitable for Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2).
Highlights
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| Species reactivity | Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2) | ||||
| Applications | ELISA, Neutralization | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | SAA2248 | ||||
| Target | HSV- gB | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| RRID | Anti-HSV-2/HHV-2 gB/Envelope glycoprotein B Antibody (SAA2248) (abinScience Cat# VK006013, RRID:AB_3730142) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Envelope glycoprotein B (gB) is a ~102 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-HSV2/HHV2 gB/Envelope glycoprotein B Antibody (SAA2248)
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