Anti-SFTSV Glycoprotein Gn Recombinant Antibody (Mab4-5) (VK662013)

Name: Anti-SFTSV Glycoprotein Gn Recombinant Antibody (Mab4-5)
Brand: abinScience
SKU: VK662013
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK662013

Description

Anti-SFTSV Glycoprotein Gn Recombinant Antibody (Mab4-5) (VK662013) is a human monoclonal antibody detecting Glycoprotein Gn in Neutralization, ELISA. Suitable for Dabie bandavirus (Severe fever with thrombocytopenia virus) (SFTSV) (Huaiyangshan banyangvirus).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Dabie bandavirus (Severe fever with thrombocytopenia virus) (SFTSV) (Huaiyangshan banyangvirus)

Applications

Neutralization, ELISA

Host species

Human

Clonality

Monoclonal

Isotype

IgG1

Clone ID

Mab4-5

Target

Gn (domain III)

Endotoxin level

< 10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-SFTSV glycoprotein Gn Antibody (Mab4-5) (abinScience Cat# VK662013, RRID:AB_3730147)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Mgp1/membrane glycoprotein polyprotein) is a ~116 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after clathrin-mediated endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins during virus assembly.

1. Hofmann, H. et al. (2013) Journal of virology 87, 4384-94. PMID: 23388721

Note

For research use only.

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References

Datasheet