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Research Grade Landogrozumab (HT343016)

Price(USD): $
Spec:
  • 100ug
  • 1mg
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  • Datasheet
Overview
Catalog No.HT343016
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHumanized
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetGDF-8, GDF8, MSTN, Myostatin, Growth/differentiation factor 8
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionO14793
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesLY-2495655, 1391726-30-9
BackgroundLandogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease.
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • Bioactivity

    SEC-HPLC detection for Research Grade Landogrozumab.

  • Flow Cytometry

    Flow-cytometry using anti-human MSTN antibody. LNCAP cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human MSTN monoclonal antibody (Catalog HT343016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

  • SDS-PAGE

    SDS-PAGE for Research Grade Landogrozumab.

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