Anti-Human DLL3 Reference Antibody (Rovalpituzumab, RUO) (HP628016)

Name: Anti-Human DLL3 Reference Antibody (Rovalpituzumab, RUO)
Brand: abinScience
SKU: HP628016
Price: 176 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	HP628016
Description	Rovalpituzumab (HP628016) is a research-grade recombinant antibody targeting Drosophila Delta homolog 3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG1-kappa
Expression system	Mammalian cells
Tested applications	FCM
Target	Drosophila Delta homolog 3, Delta3, Delta-like protein 3, DLL3
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9NYJ7
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	SC0001-SCX, SC0002, 1613313-01-1
Background	Delta-like protein 3 (DLL3) is a ~64 kDa protein. Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

Bioactivity

SEC-HPLC detection for Research Grade Rovalpituzumab.
SDS-PAGE

SDS-PAGE for Anti-Human DLL3 Reference Antibody (Rovalpituzumab, RUO)
Flow CytoMetry

Flow-cytometry using anti-human DLL3 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human DLL3 monoclonal antibody (Catalog: HP628016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.