Catalog No. | JN060016 |
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Species reactivity | Staphylococcus aureus |
Applications | ELISA, Functional assay, Research in vivo |
Host species | Humanized |
Isotype | IgG1-kappa |
Expression system | Mammalian Cells |
Clonality | Monoclonal |
Target | clfAClumping factor A |
Endotoxin level | Please contact the lab for this information. |
Purity | >95% purity as determined by SDS-PAGE. |
Purification | Protein A/G purified from cell culture supernatant. |
Accession | Q53653, Q2G015, Q5HHM8 |
Form | Liquid |
Storage buffer | 0.01M PBS, pH 7.4. |
Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names | Aurexis, 521079-87-8 |
Background | Tefibazumab is a humanized IgG1κ monoclonal antibody that binds to the surface-expressed adhesion protein clumping factor A. Tefibazumab can be used for the research of serious Staphylococcus aureus infections. • Diabetic retinopathy., PMID:22455417 • Novel Target for Limiting VEGF-A (Vascular Endothelial Growth Factor A)-Induced Vascular Permeability., PMID:36004641 • Vascular endothelial growth factor-A as a promising therapeutic target for the management of psoriasis., PMID:32654325 • Interleukin-37, vascular endothelial growth factor A, and transforming growth factor-β1: promising biomarkers in primary immune thrombocytopenia., PMID:35815383 • [Research progress of vascular endothelial growth factor-A and its isoforms in kidney disease]., PMID:35199126 • Life and Death of Podocytes: Not Only a Matter of Vascular Endothelial Growth Factor., PMID:26930245 • Preface., PMID:30612609 • Monoclonal antibodies neutralizing alpha-hemolysin, bicomponent leukocidins, and clumping factor A protected against Staphylococcus aureus-induced acute circulatory failure in a mechanically ventilated rabbit model of hyperdynamic septic shock., PMID:37781371 • Diabetic retinopathy., PMID:22784133 • Diabetic retinopathy., PMID:22784134 |
Note | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Tefibazumab.
SDS-PAGE for Research Grade Tefibazumab.
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