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Research Grade Foravirumab (VK632016)

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Research Grade Foravirumab

Research Grade Foravirumab

Research Grade Foravirumab

Research Grade Foravirumab

Research Grade Foravirumab

Research Grade Foravirumab

Price(USD): $

Spec:

100ug
1mg

Number:

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Overview
Images
References
Datasheet

Overview

Catalog No.	VK632016
Description	Foravirumab (VK632016) is a research-grade recombinant antibody targeting G/Glycoprotein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Rabies virus (RABV)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	G/Glycoprotein
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O92284
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	CR4098, 944548-38-3
Background	Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Foravirumab.
Bioactivity

Detects Human G/Glycoprotein in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Foravirumab.

References

Datasheet

Research Grade Foravirumab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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V₁ (Stock Vol.)

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Working Solution

C₂ (Working Conc.)

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Research Grade Foravirumab