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Anti-HPV18 L1/Major capsid protein L1 Reference Antibody (H18L1-A, RUO) (VK639016)

Anti-HPV18 L1/Major capsid protein L1 Reference Antibody (H18L1-A, RUO)
Anti-HPV18 L1/Major capsid protein L1 Reference Antibody (H18L1-A, RUO)
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  • Overview

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Overview
Catalog No.VK639016
Description
Anti-HPV18 L1/Major capsid protein L1 Antibody (H18L1-A) (VK639016) is a research-grade recombinant antibody targeting Major capsid protein L1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman papillomavirus 18 (HPV18)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1, kappa
Clone IDH18L1-A
Expression system Mammalian cells
Clonality Monoclonal
Target Major capsid protein L1, L1
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P06794
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Major capsid protein L1 is a ~63 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-HPV18 L1/Major capsid protein L1 Reference Antibody (H18L1-A, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-HPV18 L1/Major capsid protein L1 Antibody (H18L1-A).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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