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Research Grade Anti-Human CD200R1/OX2R Antibody (I-4P) (HV213026)

Research Grade Anti-Human CD200R1/OX2R Antibody (I-4P)
Research Grade Anti-Human CD200R1/OX2R Antibody (I-4P)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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Overview
Catalog No.HV213026
Description
Anti-Human CD200R1/OX2R Antibody (I-4P) (HV213026) is a research-grade recombinant antibody targeting CD200. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG4
Clone IDI-4P
Expression system Mammalian Cells
Clonality Monoclonal
Target MOX2R, Cell surface glycoprotein OX2 receptor 1, OX2R, Cell surface glycoprotein CD200 receptor 1, CD200R, CD200 cell surface glycoprotein receptor, CRTR2, CD200R1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q8TD46
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background

Cell surface glycoprotein CD200 receptor 1 (CD200R1/OX2R) is a ~39 kDa protein. Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Anti-Human CD200R1/OX2R Antibody (I-4P)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CD200R1/OX2R Antibody (I-4P)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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