| Catalog No. | HV802056 |
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| Species reactivity | Human |
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| Applications | ELISA, Functional assay, Research in vivo |
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| Isotype | Fc fragment of human immunoglobulin G1 fused via peptide linker to human FGF-21 fragment-variant |
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| Expression system | Mammalian Cells |
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| Target | FGF21, Fibroblast growth factor 21, FGF-21 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | Q9NSA1 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | 2765640-39-7 |
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| Background | HY-P990964 is an FGFR1-targeting human antibody.
• Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis., PMID:34530349
• Efficacy and Safety of Fibroblast Growth Factor-21 Analogs for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis: A Systematic Review and Meta-Analysis., PMID:38666606
• Fibroblast growth factor (FGF)-21 based therapies: A magic bullet for nonalcoholic fatty liver disease (NAFLD)?, PMID:31948295
• Targeting FGF21 in cardiovascular and metabolic diseases: from mechanism to medicine., PMID:36594101
• Fibroblast growth factor 21., PMID:38991938
• FGF-21 as a novel metabolic regulator., PMID:15902306
• Fibroblast growth factor 21 and bone homeostasis., PMID:35850479
• FGF21: A Novel Regulator of Glucose and Lipid Metabolism and Whole-Body Energy Balance., PMID:35413740
• Role of Fibroblast Growth Factor 21 (FGF21) in the Regulation of Statural Growth., PMID:26133178
• Fibroblast growth factor 21 in metabolic syndrome., PMID:37576954
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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