| Catalog No. | HS739266 |
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| Species reactivity | Human |
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| Applications | ELISA, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | Humanized IgG4-kappa, anti-human TIGIT fused at the C-terminusof the heavy chain, via a (G4S)4 peptide linker, to a fragment of the mature extracellular domain of human TGF-beta receptor type-2. |
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| Expression system | Mammalian Cells |
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| Target | VSTM3, TIGIT, V-set and transmembrane domain-containing protein 3, VSIG9, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains, TGFR-2, TbetaR-II, TGF-beta type II receptor, TGFBR2, TGF-beta receptor type-2, TGF-beta receptor type II, Transforming growth factor-beta receptor type II |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | Q495A1 & P37173 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | 2769742-99-4 |
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| Background | HY-P990960 is an TIGIT-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003). |
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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