| Catalog No. | HF862996 |
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| Species reactivity | Human |
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| Applications | ELISA, Functional assay, Research in vivo |
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| Isotype | Recombinant human FGF19 analogs. |
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| Expression system | Mammalian Cells |
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| Target | FGF19, Fibroblast growth factor 19, FGF-19 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Purified by Nickel column. |
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| Accession | O95750 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | NGM282 |
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| Background | Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH).
• Modulation of metabolic syndrome by fibroblast growth factor 19 (FGF19)?, PMID:15140837
• FGF19-Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of Colorectal Cancer., PMID:37345586
• The FGF family: biology, pathophysiology and therapy., PMID:19247306
• Mechanisms of Parenteral Nutrition-Associated Liver and Gut Injury., PMID:31872510
• Metabolic Messengers: fibroblast growth factor 15/19., PMID:32694803
• FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2., PMID:36907560
• Effect of Fibroblast Growth Factor (FGF) 19 and 21 on Hip Geometry and Strength in Post-menopausal Osteoporosis (PMO)., PMID:39341924
• Fibroblast growth factor 15/19 expression, regulation, and function: An overview., PMID:35301051
• Effect of Bariatric Surgery on Metabolic Diseases and Underlying Mechanisms., PMID:34827579
• Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice., PMID:28650457
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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