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Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Utomilumab, RUO) (HC336016)

Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Utomilumab, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Utomilumab, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Utomilumab, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Utomilumab, RUO)
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Overview
Catalog No.HC336016
Description
Utomilumab (HC336016) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG2-lambda
Target 4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q07011
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesPF-05082566, PF-2566, 1417318-27-4
Background

Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).

Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
Images
  • Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Utomilumab, RUO)

    Bioactivity

    Detects Human CD137/TNFRSF9/4-1BB in indirect ELISAs.

  • Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Utomilumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Utomilumab.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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