| Catalog No. | HB943016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Chimeric |
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| Isotype | IgG4-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | CD138, SDC1, SDC, Syndecan-1, SYND1 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P18827 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Background | Indatuximab is a CHO-expressed, VHH-Fc (huIgG1) type chimeric antibody that targets Syndecan-1/CD138. The predicted molecular weight (MW) of Indatuximab is 146.1 kDa. The isotype control for Indatuximab can refer to Human IgG4 kappa, Isotype Control (HY-P99003).
• CD138 (syndecan-1) expression in health and disease., PMID:24150912
• Syndecan-1 in liver pathophysiology., PMID:35704700
• Syndecan-1: A Novel Diagnostic and Therapeutic Target in Liver Diseases., PMID:37957867
• Syndecan-1: a key player in health and disease., PMID:39688651
• Soluble CD138/Syndecan-1 Increases in the Sera of Patients with Moderately Differentiated Bladder Cancer., PMID:25115297
• The heparan sulphate proteoglycan Syndecan-1 (CD138) regulates tumour progression in a 3D model of ductal carcinoma in situ of the breast., PMID:35587107
• NETs induce ferroptosis of endothelial cells in LPS-ALI through SDC-1/HS and downstream pathways., PMID:38677244
• Association of serum syndecan-1 concentrations with albuminuria in type 2 diabetes., PMID:39155787
• Correlation of Hyaluronic Acid (HA), Syndecan-1 (SDC-1), Heparan Sulfate (HS) With Early Stage End Organ Dysfunction in Sepsis Patients., PMID:39819814
• Molecular and clinical profiles of syndecan-1 in solid and hematological cancer for prognosis and precision medicine., PMID:26293675
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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