| Catalog No. | HC678016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG1-kappa |
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| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166 |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
Q13740 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | CX-2009, 2145109-70-0 |
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| Background | Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers.
• Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity., PMID:16204050
• Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients., PMID:26134500
• Predictive impact of activated leukocyte cell adhesion molecule (ALCAM/CD166) in breast cancer., PMID:18172759
• Functional polymorphisms in CD166/ALCAM gene associated with increased risk for breast cancer in a Chinese population., PMID:21293922
• Identification of clinically significant tumor antigens by selecting phage antibody library on tumor cells in situ using laser capture microdissection., PMID:16982673
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| Note |
For research use only. Not suitable for clinical or therapeutic use. |
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