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Human SEC24C Recombinant Protein (N-His) (HD071012)

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Overview
Catalog No.HD071012
Description
Recombinant Human SEC24C Protein, N-His (HD071012) expressed in E. coli, spanning Asp324-Ser1094. Purity: >90% by SDS-PAGE.
Highlights
  • His-Tagged — N-terminal 6×His tag for IMAC purification.
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% purity verified by SDS-PAGE.
Expression systemE. coli
AccessionP53992
Protein lengthAsp324-Ser1094
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 88.31 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesKIAA0079, Protein transport protein Sec24C, SEC24-related protein C, SEC24C
Background

Protein transport protein Sec24C is a ~118 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5.

1. Tani, K. et al. (1999) FEBS letters 447, 247-50. PMID: 10214955
2. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046
3. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296
4. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317
Note For research use only
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Formula
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Formula
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