Human CD2AP Recombinant Protein (N-His) (HV416042)

Name: Human CD2AP Recombinant Protein (N-His)
Brand: abinScience
SKU: HV416042
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HV416042
Description	Recombinant Human CD2AP Protein, N-His (HV416042) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9Y5K6
Protein length	Met1-Glu166
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Adapter protein CMS, CD2-associated protein, CD2AP, Cas ligand with multiple SH3 domains
Background	CD2-associated protein is a ~71 kDa protein. Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. 1. Kirsch, KH. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 6211-6. PMID: 10339567 2. Monzo, P. et al. (2005) Molecular biology of the cell 16, 2891-902. PMID: 15800069 3. Elbediwy, A. et al. (2012) The Journal of cell biology 198, 677-93. PMID: 22891260
Note	For research use only

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Datasheet

Human CD2AP Recombinant Protein (N-His).pdf

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Human CD2AP Recombinant Protein (N-His) (HV416042)

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