Mouse CCN3 Recombinant Protein (N-His) (MW350022)

Name: Mouse CCN3 Recombinant Protein (N-His)
Brand: abinScience
SKU: MW350022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MW350022
Description	Recombinant Mouse CCN3 Protein, N-His (MW350022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q64299
Protein length	Ser50-Ile354
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CCN family member 3, Ccn3, Cellular communication network factor 3, Nephroblastoma-overexpressed gene protein homolog, Nov, NovH, Protein NOV homolog
Background	CCN family member 3 is a ~38 kDa protein. Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival. Acts by binding to integrins or membrane receptors such as NOTCH1. Essential regulator of hematopoietic stem and progenitor cell function. Inhibits myogenic differentiation through the activation of Notch-signaling pathway. Inhibits vascular smooth muscle cells proliferation by increasing expression of cell-cycle regulators such as CDKN2B or CDKN1A independently of TGFB1 signaling. 1. Matsushita, Y. et al. (2013) The Journal of biological chemistry 288, 19973-85. PMID: 23653360 2. Paradis, R. et al. (2013) PloS one 8, e64957. PMID: 23705021 3. Liu, J. et al. (2014) PloS one 9, e94912. PMID: 24722330 4. Babey, ME. et al. (2024) Nature 632, 357-365. PMID: 38987585
Note	For research use only

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Datasheet

Mouse CCN3 Recombinant Protein (N-His).pdf

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Mouse CCN3 Recombinant Protein (N-His) (MW350022)

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