

| Catalog No. | HW796014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-AFM Polyclonal Antibody (HW796014) is a rabbit polyclonal antibody detecting AFM in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human AFM (Leu22-Thr210). | ||||||||
| Target | ALB2, Alpha-Alb, AFM, Alpha-albumin, ALBA, Afamin | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P43652 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Afamin (AFM) is a ~69 kDa protein. Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier. 1. Mihara, E. et al. (2016) eLife 5. PMID: 26902720 2. Voegele, AF. et al. (2002) Biochemistry 41, 14532-8. PMID: 12463752 3. Jerkovic, L. et al. (2005) Journal of proteome research 4, 889-99. PMID: 15952736 4. Kratzer, I. et al. (2009) Journal of neurochemistry 108, 707-18. PMID: 19046407 | ||||||||
| Note | For research use only. |
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