Anti-ADRA2C Recombinant Antibody (N378/107) (HB097033)

Name: Anti-ADRA2C Recombinant Antibody (N378/107)
Brand: abinScience
SKU: HB097033
Price: 196 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB097033

Description

Anti-Alpha-2C adrenergic receptor Recombinant Antibody (N378/107) (HB097033) is a mouse monoclonal antibody detecting ADRA2C in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N378/107

Target

ADRA2L2, ADRA2C, Alpha-2CAR, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2C adrenergic receptor, ADRA2RL2, Alpha-2 adrenergic receptor subtype C4

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-Alpha-2C adrenergic receptor Antibody (N378/107) (abinScience Cat# HB097033, RRID:AB_3728150)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Alpha-2C adrenergic receptor (ADRA2C) is a ~49 kDa protein. Alpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate the G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression. Control a variety of physiological processes, such as regulation of blood pressure, lipolysis and insulin release. ADRA2A and ADRA2C mediates the presynaptic feedback inhibition of neurotransmitter release from noradrenergic nerve terminals in sympathetic and central nervous systems. ADRA2A inhibits transmitter release at high stimulation frequencies, whereas ADRA2C modulates neurotransmission at lower levels of nerve activity. The rank order of potency for physiological agonists of ADRA2C is epinephrine > norepinephrine > dopamine.

1. Regan, JW. et al. (1988) Proceedings of the National Academy of Sciences of the United States of America 85, 6301-5. PMID: 2842764

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Alpha-2C adrenergic receptor Antibody (N378/107)

References

Datasheet

Anti-ADRA2C Recombinant Antibody (N378/107).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ADRA2C Recombinant Antibody (N378/107) (HB097033)

Overview

Images

References

Datasheet

SDS