Anti-Alphaherpesviruses gB Broad-Neutralizing Recombinant Antibody (16F9) (VK006073)

Name: Anti-Alphaherpesviruses gB Broad-Neutralizing Recombinant Antibody (16F9)
Brand: abinScience
SKU: VK006073
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK006073

Description

Anti-Alphaherpesviruses gB Broad-Neutralizing Recombinant Antibody (16F9) (VK006073) is a mouse monoclonal antibody detecting gB in ELISA, SPR, IF, FCM. Suitable for Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2), Varicella-zoster virus (HHV-3) (Human herpesvirus 3), Suid herpesvirus 1 (SuHV-1) (Pseudorabies virus), Bovine herpesvirus 1 (BoHV-1), Bovine herpesvirus 2 (BoHV-2), Bovine herpesvirus 5 (BoHV-5).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2), Varicella-zoster virus (HHV-3) (Human herpesvirus 3), Suid herpesvirus 1 (SuHV-1) (Pseudorabies virus), Bovine herpesvirus 1 (BoHV-1), Bovine herpesvirus 2 (BoHV-2), Bovine herpesvirus 5 (BoHV-5)

Applications

ELISA, SPR, IF, FCM

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

16F9

Target

gB, Envelope glycoprotein B

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelope glycoprotein B (gB) is a ~102 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.

Note

For research use only.

Images

References

Datasheet

Anti-Alphaherpesviruses gB Broad-Neutralizing Recombinant Antibody (16F9).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Alphaherpesviruses gB Broad-Neutralizing Recombinant Antibody (16F9) (VK006073)

Overview

Images

References

Datasheet

SDS