

| Catalog No. | HF579013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-BAF53a Recombinant Antibody (N336B/26) (HF579013) is a mouse monoclonal antibody detecting ACTL6A/BAF53a in IHC, WB.
Highlights
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| Applications | IHC, WB | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | N336B/26 | ||||
| Target | BAF53, BAF53A, INO80K, BRG1-associated factor 53A, ArpNbeta, Actin-related protein Baf53a, INO80 complex subunit K, ACTL6A, Actin-like protein 6A, 53 kDa BRG1-associated factor A | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| RRID | Anti-BAF53a Antibody (N336B/26) (abinScience Cat# HF579013, RRID:AB_3728086) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Actin-like protein 6A (ACTL6A/BAF53a) is a ~47 kDa protein. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-BAF53a Antibody (N336B/26)
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