Anti-BKPyV Major capsid protein VP1 Recombinant Antibody (MTX-005) (VK452013)

Name: Anti-BKPyV Major capsid protein VP1 Recombinant Antibody (MTX-005)
Brand: abinScience
SKU: VK452013
Price: 191 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK452013

Species reactivity

BK polyomavirus (BKPyV)

Applications

ELISA, FACS, Functional assay

Host species

Human

Isotype

IgG

Clone ID

MTX-005

Clonality

Monoclonal

Target

Major capsid protein VP1, Major structural protein VP1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P14996

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Major capsid protein VP1 is a ~40 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with gangliosides GT1b and GD1b containing terminal alpha(2-8)-linked sialic acids on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.

Note

For research use only

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