Anti-BVDV NS4B Recombinant Nanobody (SAA2612) (VK778063)

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50ug
100ug
1mg

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Overview
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Datasheet
SDS

Overview

Catalog No.

VK778063

Description

Anti-BVDV NS4B Nanobody (SAA2612) [SAA2612] (VK778063) is a alpaca monoclonal antibody detecting NS4B in ELISA, IF, WB.

Highlights

●Multi-Application — Validated across multiple applications.

Species reactivity

Bovine viral diarrhea virus 1 (BVDV1)

Applications

ELISA, IF, WB

Host species

Alpaca

Isotype

VHH-His

Clone ID

SAA2612

Clonality

Monoclonal

Target

Autoprotease p20, Capsid protein C, Cysteine protease NS2, E(rns) glycoprotein, EC:2.7.7.48, EC:3.4.21.113, EC:3.4.22.-, EC:3.6.1.15, EC:3.6.4.13, EC:4.6.1.19, Envelope glycoprotein E1, Envelope glycoprotein E2, Genome polyprotein, N-pro, N-terminal protease, NS4A, NS4B, NS5A, NS5B, Non-structural protein 2, Non-structural protein 2-3, Non-structural protein 3, Non-structural protein 4A, Non-structural protein 4B, Non-structural protein 5A, RNA-directed RNA polymerase, Serine protease NS3, Viroporin p7, gp33, gp44/48, gp55, p10, p14, p30, p54, p58, p75, p80

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P19711

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Genome polyprotein (NS4B) is a ~449 kDa protein. Leader cysteine autoprotease that cleaves itself from the nascent polyprotein during translation of the viral mRNA. Once released, plays a role in the inhibition of host innate immune response by interacting with host IRF3 and inducing its proteasomal degradation.

1. Chen, Z. et al. (2007) Virology 366, 277-92. PMID: 17531282

Note

For research use only

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References

Datasheet