Anti-CALM1 Polyclonal Antibody (HY390014)

Name: Anti-CALM1 Polyclonal Antibody
Brand: abinScience
SKU: HY390014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY390014

Description

Anti-CALM1 Polyclonal Antibody (HY390014) is a rabbit polyclonal antibody detecting CALM1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Achlya klebsiana, and Agaricus bisporus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CALM1 (Ala2-Lys149).

Target

CAM1, CALM1, CAM, CALM, Calmodulin-1

Purification

Purified by antigen affinity column.

Accession

P0DP23

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Calmodulin-1 (CALM1) is a ~16 kDa protein. Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Is a regulator of voltage-dependent L-type calcium channels.

1. Tsang, WY. et al. (2006) Molecular biology of the cell 17, 3423-34. PMID: 16760425

2. Reichow, SL. et al. (2013) Nature structural & molecular biology 20, 1085-92. PMID: 23893133

3. Boczek, NJ. et al. (2016) Circulation. Cardiovascular genetics 9, 136-146. PMID: 26969752

4. Yu, CC. et al. (2016) Heart rhythm 13, 1716-23. PMID: 27165696

5. Zhao, YG. et al. (2017) Molecular cell 67, 974-989.e6. PMID: 28890335

6. Wren, LM. et al. (2019) Circulation. Genomic and precision medicine 12, 375-385. PMID: 31454269

7. Alphonse, N. et al. (2022) Cell 185, 2354-2369.e17. PMID: 35568036

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CALM1 polyclonal antibody at 1ug/mL on recombinant CALM1 (Catalog No. HY390012).

References

Datasheet

Anti-CALM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CALM1 Polyclonal Antibody (HY390014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us