Anti-Feline Beta-NGF Recombinant Antibody (SAA1471) (FF909023)

Name: Anti-Feline Beta-NGF Recombinant Antibody (SAA1471)
Brand: abinScience
SKU: FF909023
Price: 110 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

FF909023

Description

Anti-Feline Beta-NGF Recombinant Antibody (SAA1471) (FF909023) is a feline monoclonal antibody detecting beta-NGF in ELISA. Suitable for Feline.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Species reactivity

Feline

Applications

ELISA

Host species

Feline

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

SAA1471

Target

Beta-NGF, Beta-nerve growth factor, NGF, NGFB

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q6ZY27

RRID

Anti-Cat NGF/Beta-NGF Antibody (SAA1471) (abinScience Cat# FF909023, RRID:AB_3727136)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Beta-nerve growth factor (Beta-nerve growth factor,NGFB,Beta-NGF,NGF) is a ~26 kDa protein. Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (Probable). The immature NGF precursor (proNGF) functions as a ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI.

1. Einarsdottir, E. et al. (2004) Human molecular genetics 13, 799-805. PMID: 14976160

2. Carvalho, OP. et al. (2011) Journal of medical genetics 48, 131-5. PMID: 20978020

3. Wijeyewickrema, LC. et al. (2010) The Journal of biological chemistry 285, 11793-9. PMID: 20164177

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Cat NGF/Beta-NGF Antibody (SAA1471).

References

Datasheet

Anti-Feline Beta-NGF Recombinant Antibody (SAA1471).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Feline Beta-NGF Recombinant Antibody (SAA1471) (FF909023)

Overview

Images

References

Datasheet

SDS