Anti-CCHFV Glycoprotein C/Gc Recombinant Antibody (SAA2435) (VK608013)

Name: Anti-CCHFV Glycoprotein C/Gc Recombinant Antibody (SAA2435)
Brand: abinScience
SKU: VK608013
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK608013

Species reactivity

Crimean-Congo hemorrhagic fever virus (CCHFV)

Applications

ELISA, Neutralization, WB, IF

Host species

Human

Isotype

IgG1, kappa

Clone ID

SAA2435

Clonality

Monoclonal

Target

Envelopment polyprotein, M polyprotein, Mucin-like variable region, GP38, Glycoprotein N, Gn, 37 kDa protein, Glycoprotein G2, Non-Structural protein M, NSm, 15 kDa protein, Glycoprotein C, Gc, 75 kDa protein, Glycoprotein G1, GP

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8JSZ3

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Glycoprotein C/Gc) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state.

1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887

2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291

3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-CCHFV Glycoprotein C/Gc Recombinant Antibody (SAA2435)

References

Datasheet

Anti-CCHFV Glycoprotein C/Gc Recombinant Antibody (SAA2435).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CCHFV Glycoprotein C/Gc Recombinant Antibody (SAA2435) (VK608013)

Overview

Images

References

Datasheet

SDS

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