Anti-CCL5 Polyclonal Antibody (HY346014)

Name: Anti-CCL5 Polyclonal Antibody
Brand: abinScience
SKU: HY346014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HY346014

Description

Anti-CCL5 Polyclonal Antibody (HY346014) is a rabbit polyclonal antibody detecting CCL5 in ELISA, IHC, WB. Suitable for Human, Cavia porcellus, and Macaca mulatta.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Cavia porcellus, Macaca mulatta

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CCL5 (Ser24-Ser91).

Target

TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP

Purification

Purified by antigen affinity column.

Accession

P13501

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064

2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218

3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620

4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373

5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414

6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CCL5 polyclonal antibody at 1ug/mL on recombinant CCL5 (Catalog No. HY346012).

References

Datasheet

Anti-CCL5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-CCL5 Polyclonal Antibody (HY346014)

Overview

Images

References

Datasheet

SDS

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