Anti-CCL7/MCP-3 Polyclonal Antibody (HX155014)

Name: Anti-CCL7/MCP-3 Polyclonal Antibody
Brand: abinScience
SKU: HX155014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HX155014

Description

Anti-CCL7/MCP-3 Polyclonal Antibody (HX155014) is a rabbit polyclonal antibody detecting MCP-3 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CCL7/MCP-3 (Gln24-Leu99).

Target

C-C motif chemokine 7, MCP-3, CCL7, Monocyte chemotactic protein 3, Monocyte chemoattractant protein 3, NC28, Small-inducible cytokine A7, SCYA6, SCYA7, MCP3

Purification

Purified by antigen affinity column.

Accession

P80098

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

C-C motif chemokine 7 (CCL7/MCP-3) is a ~11 kDa protein. Chemotactic factor that plays an important role in immune regulation. Attracts monocytes, eosinophils, basophils, and T-cells to sites of inflammation or infection. Upon binding to various chemokine receptors including CCR1, CCR2, CCR3, and CCR5, facilitates immune cell migration by guiding them to infected tissues. Interacts with CCR2 to facilitate the release of monocytes from the bone marrow into the bloodstream, maintaining monocyte homeostasis. In turn, monocytes recruited to inflamed or injured tissues can differentiate into macrophages or dendritic cells, which are essential for immune defense and tissue repair.

1. Bonini, JA. et al. (1997) DNA and cell biology 16, 1249-56. PMID: 9364936

2. Blanpain, C. et al. (1999) Blood 94, 1899-905. PMID: 10477718

3. Wei, H. et al. (2024) Cellular signalling 117, 111122. PMID: 38417634

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CCL7/MCP-3 polyclonal antibody at 1ug/mL on recombinant CCL7/MCP-3 (Catalog No. HX155012).

References

Datasheet

Anti-CCL7/MCP-3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-CCL7/MCP-3 Polyclonal Antibody (HX155014)

Overview

Images

References

Datasheet

SDS

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