Anti-CD66b/CEACAM8 Polyclonal Antibody (HB202014)

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Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB202014

Description

Anti-CD66b/CEACAM8 Polyclonal Antibody (HB202014) is a rabbit polyclonal antibody detecting CEACAM8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD66b/CEACAM8 (Gln35-Asp320).

Target

CD67 antigen, Carcinoembryonic antigen CGM6, Carcinoembryonic antigen-related cell adhesion molecule 8, CGM6, CD66b, Non-specific cross-reacting antigen NCA-95, CEACAM8

Purification

Purified by antigen affinity column.

Accession

P31997

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cell adhesion molecule CEACAM8 (CD66b) is a ~38 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.

1. Kuroki, M. et al. (2001) Journal of leukocyte biology 70, 543-50. PMID: 11590190

2. Oikawa, S. et al. (1991) The Journal of biological chemistry 266, 7995-8001. PMID: 2022629

3. Yamanaka, T. et al. (1996) Protein expression and purification 7, 438-46. PMID: 8776764

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD66b/CEACAM8 polyclonal antibody at 1ug/mL on recombinant CD66b/CEACAM8 (Catalog No. HB202012).

References

Datasheet