Anti-DLL4 Polyclonal Antibody (HV571014)

Name: Anti-DLL4 Polyclonal Antibody
Brand: abinScience
SKU: HV571014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV571014

Description

Anti-DLL4 Polyclonal Antibody (HV571014) is a rabbit polyclonal antibody detecting DLL4 in ELISA, IHC, WB. Suitable for Human and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DLL4 (Leu16-Ala539).

Target

Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4

Purification

Purified by antigen affinity column.

Accession

Q9NR61

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types.

1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954

2. Brütsch, R. et al. (2010) Circulation research 107, 592-601. PMID: 20616313

3. Del Barrio, MG. et al. (2007) Development (Cambridge, England) 134, 3427-36. PMID: 17728344

Note

For research use only.

Images

References

Datasheet