Anti-Dupilumab Neutralizing Recombinant Antibody (SAA2183) (AB732023)

Name: Anti-Dupilumab Neutralizing Recombinant Antibody (SAA2183)
Brand: abinScience
SKU: AB732023
Price: 168 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

AB732023

Description

Anti-Dupilumab Neutralizing Recombinant Antibody (SAA2183) (AB732023) is a rabbit monoclonal antibody detecting Dupilumab in ELISA, Neutralization. Suitable for General.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

General

Applications

ELISA, Neutralization

Host species

Rabbit

Clonality

Monoclonal

Isotype

IgG

Clone ID

SAA2183

Expression system

Mammalian cells

Immunogen

Dupilumab

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

CAS: 1190264-60-8

RRID

Anti-Dupilumab Neutralizing Antibody (SAA2183) (abinScience Cat# AB732023, RRID:AB_3729584)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Interleukin-4 receptor subunit alpha (Dupilumab) is a ~89 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

1. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Dupilumab Neutralizing Antibody (SAA2183)

References

Datasheet

Anti-Dupilumab Neutralizing Recombinant Antibody (SAA2183).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Dupilumab Neutralizing Recombinant Antibody (SAA2183) (AB732023)

Overview

Images

References

Datasheet

SDS