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Anti-Dupilumab Polyclonal Antibody (AB732014)

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Overview
Catalog No.AB732014
Description
Anti-Dupilumab Polyclonal Antibody (AB732014) is a rabbit polyclonal antibody detecting Dupilumab in ELISA.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen Dupilumab
Target Rabbit polyclonal to Dupixent.
Specificity The product is specific for Dupilumab. This antibody serves as an excellent positive control for Dupilumab immunogenicity (ADA) assays.
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession CAS: 1190264-60-8
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundDupilumab with trade name Dupixent, is an FDA-approved drug for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4Rα) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling. Anti-Dupilumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Dupilumab.
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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