Anti-EAAC1 Recombinant Antibody (N420/26) (HW669023)

Name: Anti-EAAC1 Recombinant Antibody (N420/26)
Brand: abinScience
SKU: HW669023
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW669023

Description

Anti-EAAC1 Recombinant Antibody (N420/26) (HW669023) is a mouse monoclonal antibody detecting SLC1A1 in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N420/26

Target

EAAC1, EAAT3, Sodium-dependent glutamate/aspartate transporter 3, Solute carrier family 1 member 1, Excitatory amino-acid carrier 1, SLC1A1, Excitatory amino acid transporter 3, Neuronal and epithelial glutamate transporter

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-EAAC1 Antibody (N420/26) (abinScience Cat# HW669023, RRID:AB_3728222)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Excitatory amino acid transporter 3 (SLC1A1) is a ~57 kDa protein. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli.

1. Bailey, CG. et al. (2011) The Journal of clinical investigation 121, 446-53. PMID: 21123949

2. Abousaab, A. et al. (2016) The Journal of membrane biology 249, 239-49. PMID: 26690923

3. Qiu, B. et al. (2021) Science advances 7. PMID: 33658209

4. Arriza, JL. et al. (1994) The Journal of neuroscience : the official journal of the Society for Neuroscience 14, 5559-69. PMID: 7521911

5. Kanai, Y. et al. (1994) The Journal of biological chemistry 269, 20599-606. PMID: 7914198

6. Zerangue, N. et al. (1996) Nature 383, 634-7. PMID: 8857541

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-EAAC1 Antibody (N420/26)

References

Datasheet

Anti-EAAC1 Recombinant Antibody (N420/26).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-EAAC1 Recombinant Antibody (N420/26) (HW669023)

Overview

Images

References

Datasheet

SDS