Anti-HHV-5/HCMV gB/Envelope glycoprotein B Recombinant Antibody (3-15#) (VK665023)

Name: Anti-HHV-5/HCMV gB/Envelope glycoprotein B Recombinant Antibody (3-15#)
Brand: abinScience
SKU: VK665023
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK665023

Species reactivity

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

Applications

ELISA, FCM, IF, WB

Host species

Human

Isotype

IgG1

Clone ID

3-15#

Clonality

Monoclonal

Target

gB, UL55, Envelope glycoprotein B

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06473

RRID

Anti-HHV-5/HCMV gB/Envelope glycoprotein B Antibody (3-15#) (abinScience Cat# VK665023, RRID:AB_3727214)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Envelope glycoprotein B (gB) is a ~102 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.

Note

For research use only.

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