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Anti-HHV-5/HCMV UL130 Recombinant Antibody (8I21#) (VK480013)

Anti-HHV-5/HCMV UL130 Recombinant Antibody (8I21#)
Anti-HHV-5/HCMV UL130 Recombinant Antibody (8I21#)
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Overview
Catalog No.VK480013
Species reactivityHuman adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
ApplicationsFCM, Neutralization
Host speciesHuman
IsotypeIgG1
Clone ID8I21#
Clonality Monoclonal
Target Envelope glycoprotein UL130
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession F5HCP3
RRID Anti-HHV-5/HCMV UL130 Antibody (8I21#) (abinScience Cat# VK480013, RRID:AB_3727215)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Envelope glycoprotein UL130 is a ~24 kDa protein. Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection.

1. Ryckman, BJ. et al. (2008) Journal of virology 82, 60-70. PMID: 17942555
2. Nogalski, MT. et al. (2013) PLoS pathogens 9, e1003463. PMID: 23853586
3. Chandramouli, S. et al. (2017) Science immunology 2. PMID: 28783665
4. Martinez-Martin, N. et al. (2018) Cell 174, 1158-1171.e19. PMID: 30057110
Note For research use only.
Images
  • Anti-HHV-5/HCMV UL130 Recombinant Antibody (8I21#)

    SDS-PAGE

    SDS-PAGE for Anti-HHV-5/HCMV UL130 Antibody (8I21#)

References
Formula
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