

| Catalog No. | VK480013 |
|---|---|
| Species reactivity | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) |
| Applications | FCM, Neutralization |
| Host species | Human |
| Isotype | IgG1 |
| Clone ID | 8I21# |
| Clonality | Monoclonal |
| Target | Envelope glycoprotein UL130 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | F5HCP3 |
| RRID | Anti-HHV-5/HCMV UL130 Antibody (8I21#) (abinScience Cat# VK480013, RRID:AB_3727215) |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Envelope glycoprotein UL130 is a ~24 kDa protein. Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. 1. Ryckman, BJ. et al. (2008) Journal of virology 82, 60-70. PMID: 17942555 2. Nogalski, MT. et al. (2013) PLoS pathogens 9, e1003463. PMID: 23853586 3. Chandramouli, S. et al. (2017) Science immunology 2. PMID: 28783665 4. Martinez-Martin, N. et al. (2018) Cell 174, 1158-1171.e19. PMID: 30057110 |
| Note | For research use only. |

SDS-PAGE for Anti-HHV-5/HCMV UL130 Antibody (8I21#)



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