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Anti-HHV-5/HCMV UL130 Polyclonal Antibody (VK480014)

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Overview
Catalog No.VK480014
Description
Anti-HHV-5/HCMV UL130 Polyclonal Antibody (VK480014) is a rabbit polyclonal antibody detecting UL130. Suitable for Human cytomegalovirus.
Species reactivityHuman cytomegalovirus (HCMV) (HHV-5) (Human herpesvirus 5)
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant HHV-5/HCMV UL130 (Ser26-Val214).
Target Envelope glycoprotein UL130, UL130
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession F5HCP3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Envelope glycoprotein UL130 is a ~24 kDa protein. Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection.

1. Ryckman, BJ. et al. (2008) Journal of virology 82, 60-70. PMID: 17942555
2. Nogalski, MT. et al. (2013) PLoS pathogens 9, e1003463. PMID: 23853586
3. Chandramouli, S. et al. (2017) Science immunology 2. PMID: 28783665
4. Martinez-Martin, N. et al. (2018) Cell 174, 1158-1171.e19. PMID: 30057110
Note For research use only
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Formula
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Anti-HHV-5/HCMV UL130 Polyclonal Antibody

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