Anti-HMPV M2/Protein M2-2 Polyclonal Antibody (VK420014)

Name: Anti-HMPV M2/Protein M2-2 Polyclonal Antibody
Brand: abinScience
SKU: VK420014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

VK420014

Species reactivity

Human metapneumovirus (HMPV)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant HMPV M2/Protein M2-2 (Thr2-Ser71).

Target

Protein M2-2, M2

Purification

Purified by antigen affinity column.

Accession

Q6WB96

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protein M2-2 is a ~8 kDa protein. Mediates the regulatory switch from transcription to RNA replication. Acts late in infection by inhibiting viral transcription and up-regulating RNA replication. Plays a major role in antagonizing the type I IFN-mediated antiviral response. Interacts with host MAVS and prevents the interaction with its upstream partner RIGI in the signaling pathway leading to interferon production. Inhibits host RIGI signaling by preventing TRIM25-mediated RIGI ubiquitination.

1. Ren, J. et al. (2012) Journal of virology 86, 13049-61. PMID: 23015697

2. Tanaka, Y. et al. (2022) Frontiers in immunology 13, 970750. PMID: 36045682

3. Ren, J. et al. (2014) PloS one 9, e91865. PMID: 24618691

4. Kitagawa, Y. et al. (2017) Journal of virology 91. PMID: 28768858

Note

For research use only.

Images

References

Datasheet

Anti-HMPV M2/Protein M2-2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-HMPV M2/Protein M2-2 Polyclonal Antibody (VK420014)

Overview

Images

References

Datasheet

SDS

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