Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP (HP849143)

Name: Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP
Brand: abinScience
SKU: HP849143
Price: 268 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50T
100T

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HP849143
Description	Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP (HP849143) is a mouse monoclonal antibody detecting Abeta 42/Beta-APP 42 in FCM. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●PerCP Conjugated — Ready for direct detection without secondary antibody.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG1
Clone ID	21F12
Conjugation	PerCP
Target	Abeta42, Beta-APP42, Amyloid-beta protein 42, amyloid beta A4 precursor protein, Amyloid-beta A4 protein, Abeta 1-42
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Associated products	Mouse IgG1 kappa Recombinant Isotype Control Antibody (HyHEL-10), PerCP
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05067
RRID	Anti-Human Abeta42/Beta-APP42 Antibody (21F12), PerCP (abinScience Cat# HP849143, RRID:AB_3725381)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Amyloid-beta precursor protein (Abeta 42/Beta-APP 42) is a ~86 kDa protein. Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(o) and JIP. 1. Baumkötter, F. et al. (2014) The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 11159-72. PMID: 25122912 2. Satpute-Krishnan, P. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 16532-7. PMID: 17062754 3. Seamster, PE. et al. (2012) Physical biology 9, 055005. PMID: 23011729
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

References

Datasheet

Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP (HP849143)

Overview

Images

References

Datasheet

SDS