Anti-Human AGTR2/AT2 Recombinant Antibody (4A03), APC (HW681137)

Name: Anti-Human AGTR2/AT2 Recombinant Antibody (4A03), APC
Brand: abinScience
SKU: HW681137
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	HW681137
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	4A03
Conjugation	APC
Clonality	Monoclonal
Target	AGTR2, Angiotensin II type-2 receptor, Type-2 angiotensin II receptor, AT2
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession	P50052
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Type-2 angiotensin II receptor (AGTR2/AT2) is a ~41 kDa protein. Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. 1. Zhang, H. et al. (2017) Nature 544, 327-332. PMID: 28379944 2. Asada, H. et al. (2018) Nature structural & molecular biology 25, 570-576. PMID: 29967536 3. Asada, H. et al. (2020) Structure (London, England : 1993) 28, 418-425.e4. PMID: 31899086 4. Tsuzuki, S. et al. (1994) Biochemical and biophysical research communications 200, 1449-54. PMID: 8185599 5. Nouet, S. et al. (2004) The Journal of biological chemistry 279, 28989-97. PMID: 15123706
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human AGTR2/AT2 Recombinant Antibody (4A03), APC.pdf

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Anti-Human AGTR2/AT2 Recombinant Antibody (4A03), APC (HW681137)

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